![]() MMD is closely related to human ADAM 11, ADAM 22, and ADAM 23, which are all important for nervous system development. MMD is highly expressed in the nervous system and underneath the cuticle, especially during the late embryonic stage and pupal stage. The objective of this research is to determine the function of the ADAM protein encoded by the mind-meld (mmd) gene in Drosophila using a loss-of-function genetic approach. ADAM (A Disintegrin And Metalloprotease) proteins are transmembrane proteins important for nervous system function, cancer metastasis, fertilization, and transitions from epithelial to mesenchymal states.
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